Endocrine Abstracts

Introduction: Russell’s Viper is a venomous snake found in South and South East Asia. The snake bite causes coagulopathy, neurotoxicity, renal failure, local effects and even death. But hypopituitarism is an extremely rare complication1. There are only a few case reports from India and Burma and we report the first case from Sri Lanka.Case report: A 49 year old man from a remote part of Sri Lanka was bitten by a Russell’s viper 3 yea...

Background: While pituitary adenomas are the commonest Sella neoplasm, number of other entities should be considered in the differential diagnosis and the diagnosis is based on histopathological and immunohistochemical characteristics. Pituitary tumors with papillary architecture are uncommon and have limited differential diagnoses. Primary papillary epithelial tumor of the pituitary is a recently described histopathological entity with striking papillary architecture and TTF1...

Turner syndrome (TS) is the most common chromosomal anomaly in females and its occurrence is about 1:4000 live births. This is the only monomer disease that humans can survive (1). It is characterized by the presence of one X chromosome and a partial or complete loss of the second X chromosome. Clinical features of TS can vary, mainly classified into Growth failure, gonadal insufficiency, cardiovascular diseases, or learning disabilities. Short stature is the only phenotypic a...

Introduction: Pituitary apoplexy is an endocrinological emergency that can be life-threatening if treatment is delayed. Apoplexy occurs either due to haemorrhage or infarction of a pituitary tumour.Case History: A 19-year-old male, presented with a sudden severe headache and visual disturbances. The examination was normal with stable haemodynamic parameters and tanner staging 5. An urgent MRI pituitary revealed a haemorrhagic pituitary macroadenoma compr...

Introduction: Graves thyrotoxicosis can be life-threatening if uncontrolled. Resistant thyrotoxicosis is not uncommon and may require urgent intervention. We present a case with severe refractory thyrotoxicosis which required urgent total thyroidectomy following bridging plasma exchange.Case History: A 35-year-old male with Grave’s disease presented with persistent thyrotoxic symptoms despite medical management for 10 months. Clinically he was hyper...

Introduction: Hyponatremia in patients with pituitary tumours are common due to many reasons including secondary hypoadrenalism and secondary hypothyroidism. When these causes are treated with the background of hyponatremia, serum sodium should be regularly monitored as it could get corrected too rapidly leading to ODS.Case report: 34 Year old patient presented to a tertiary care hospital with headache. His MRI brain revealed a large suprasellar lesion s...